Denigma

gcy-18

Symbol: gcy-18
Name: Guanylyl CYclase 18
Entrez gene ID: 178237
Ensembl gene ID: ZK896.8
Species: Worm (Taxid: 6239)

Functional description:
Protein GCY-18; Guanylyl CYclase family member (gcy-18) [Source:RefSeq peptide;Acc:NP_502449] [Ensembl]

Observation:

RNAi of gcy-18 increases mean lifespan by 25%. gcy-18 expression is repressed by daf-2 RNAi, but induced by combined RNAi of daf-16 and daf-2 [12845331].



Interventions:
  • gcy-18 RNAi +25%

    • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • gcy-29 (6239)
  • gcy-18 (6239)
  • gcy-23 (6239)
  • gcy-9 (6239)
  • gcy-25 (6239)
  • gcy-8 (6239)



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