aakg-2

Symbol: aakg-2
Name: AMP-Activated protein Kinase Gamma subunit 2
Alias: sta-2
Entrez gene ID: 181736
Ensembl gene ID: T20F7.6
Species: Worm (Taxid: 6239)

Functional description:
Protein AAKG-2; Protein AAKG-2 [Source:UniProtKB/TrEMBL;Acc:O02168] [Ensembl]; aakg-2 encodes one of five C. elegans AMP kinase (AMPK) gamma regulatory subunits. [WormBase]

Observation:

aakg-2 overexpression extends mean, median, and maximum lifespan by 47, 45, and 35%. Overexpression of aakg-2 toegther with D. rerio ucp2 was non-additive with sDR [22737090].



Interventions:
  • aakg-2 overexpression +47% +45% +35%

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • Y41G9A.3 (6239)
  • T20F7.6 (6239)



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