CPR7

Symbol: CPR7
Name: Cyclosporin-sensitive Proline Rotamase 7
Entrez gene ID: 853489
Ensembl gene ID: YJR032W
Species: Yeast (Taxid: 4932)

Functional description:
Cpr7p; Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity [Source:SGD;Acc:S000003793] [Ensembl]

Observation:

Deletion of CPR7 has no effect on lifespan replicative lifespan, but increases chronological lifespan [11361336]



Interventions:
  • CPR7 deletion

  • Assays: Replicative Lifespan Chronological Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CPR7 (4932)
  • KLLA0E22705g (28985)
  • AGOS_AEL062C (33169)

  • Note: Different effects on replicative and chronological lifespan.

    Edit \ Update (Admin) | Delete

    Comment on This Data Unit