Denigma

sgg

Symbol: sgg
Name: shaggy
Entrez gene ID: 31248
Ensembl gene ID: FBgn0003371
Species: Fly (Taxid: 7227)

Functional description:
Required for several developmental events such as synctial blastoderm formation and embryonic segmentation. Is involved in transcriptional regulation. Required for Arm phosphorylation. Wg signaling operates by inactivating the Sgg repression of en autoactivation. [UniProt]

Observation:

Several insertions of P-based vectors in the structural part of sgg are associated with alterations of male and female lifespan [22661237].



Interventions:
  • sgg transposition

    • Assays: Organismal Lifespan

    Classification:
  • Aging Associated


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • GSK3B (9606)
  • GSK3B (9598)
  • GSK3B (9615)
  • GSK3B (9913)
  • Gsk3b (10090)
  • Gsk3b (10116)
  • GSK3B (9031)
  • gsk3b (7955)
  • sgg (7227)
  • AgaP_AGAP004443 (7165)
  • gsk-3 (6239)
  • SK13 (3702)
  • Os05g0134000 (4530)
  • PfGSK-3 (5833)

    • Inparanoids
  • SPAC1F3.02c (4896)



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