Denigma

CKB2

Symbol: CKB2
Name: Casein Kinase Beta' subunit
Alias: CK2 subunit
Entrez gene ID: 854204
Ensembl gene ID: YOR039W
Species: Yeast (Taxid: 4932)

Functional description:
Ckb2p; Beta' regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase [Source:SGD;Acc:S000005565] [Ensembl]

Observation:

Lack of Ckb2 promotes a modest but significant chronological lifespan extension and marked increase in yeat resistance [20657825].



Interventions:
  • CKB2 deletion

    • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • CSNK2B (9606)
  • CSNK2B (9615)
  • CSNK2B (9913)
  • Csnk2b (10090)
  • Csnk2b (10116)
  • ck2b (7955)
  • LOC557674 (7955)
  • CkIIbeta (7227)
  • kin-10 (6239)
  • ckb1 (4896)
  • CKB2 (4932)
  • KLLA0E21869g (28985)
  • AGOS_ACR087C (33169)
  • GeneID:2676027 (148305)
  • NCU02754 (5141)
  • CKB3 (3702)
  • CKB4 (3702)



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