E01A2.2

Symbol: E01A2.2
Entrez gene ID: 171996
Ensembl gene ID: E01A2.2
Species: Worm (Taxid: 6239)

Functional description:
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). [UniProt]

Observation:

RNAi against E01A2.2 increases mean and maximum lifespan by 11 and 18%, respectively [19293945].



Interventions:
  • E01A2.2 RNAi +11% +18%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SRRT (9606)
  • SRRT (9615)
  • SRRT (9913)
  • Srrt (10090)
  • srrt (7955)
  • CG7843 (7227)
  • AgaP_AGAP010382 (7165)
  • E01A2.2 (6239)



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