Symbol: E01A2.2 Entrez gene ID: 171996 Ensembl gene ID: E01A2.2 Species: Worm (Taxid: 6239) Functional description: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). [UniProt] Observation: RNAi against E01A2.2 increases mean and maximum lifespan by 11 and 18%, respectively [19293945]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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