mak-2

Symbol: mak-2
Name: MAP kinase Activated protein Kinase
Entrez gene ID: 176914
Ensembl gene ID: C44C8.6
Species: Worm (Taxid: 6239)

Functional description:
Protein MAK-2; MAP kinase Activated protein Kinase family member (mak-2) [Source:RefSeq peptide;Acc:NP_500005] [Ensembl]; mak-2 encodes a serine/threonine protein kinase that is orthologous to the vertebrate MAPKAPK2 and MAPKAPK3 (MAP kinase-activated protein kinase family members 2 and 3) kinases. [WormBase]

Observation:

RNAi of mak-2 increases mean and maximum lifespan by 12 and 14% [19293945].



Interventions:
  • mak-2 RNAi +12% +14%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MAPKAPK3 (9606)
  • MAPKAPK3 (9598)
  • MAPKAPK3 (9615)
  • MAPKAPK3 (9913)
  • Mapkapk3 (10090)
  • Mapkapk3 (10116)
  • MAPKAPK3 (9031)
  • mapkapk3 (7955)
  • MAPk-Ak2 (7227)
  • AgaP_AGAP011890 (7165)
  • mak-2 (6239)



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