Symbol: GSTZ1 Name: glutathione transferase zeta 1 Alias: GSTZ1-1;MAAI;MAI;MGC2029;LOC2954 Entrez gene ID: 2954 Ensembl gene ID: ENSG00000100577 Species: Human (Taxid: 9606) Functional description: Bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4- nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T- butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. [UniProt] Observation: rs21116999 located in intron 1 of the GSTZ1 gene was significantly associated with longevity in a population Calabria (Italy).GSTZ1 was found to be associated with longevity [22576335]. Assays: Organismal Lifespan Longevity Associated Variants: Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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