Symbol: tbp-1 Name: TATA-Binding Protein Entrez gene ID: 176054 Ensembl gene ID: T20B12.2 Species: Worm (Taxid: 6239) Functional description: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. [UniProt] Observation: RNAi against tbp-1 decreases mean and maximum lifespan by 15-27% and 21%, respectively [18059442]. Interventions: Assays: Organismal Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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