prx-13

Symbol: prx-13
Name: PeRoXisome assembly factor
Entrez gene ID: 174192
Ensembl gene ID: F32A5.6
Species: Worm (Taxid: 6239)

Functional description:
Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5) (By similarity). [UniProt]

Observation:

Knockdown of prx-13 increases mean and maximum lifespan by 17% (28%!) and 11% respectively. prx-13 knockdown from hatching does no effect [22509016].



Interventions:
  • prx-13 RNAi +28% +11%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • References:
  • 22509016: Midlife gene expressions identify modulators of aging through dietary interventions.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PEX13 (9606)
  • PEX13 (9598)
  • PEX13 (9615)
  • PEX13 (9913)
  • Pex13 (10090)
  • Pex13 (10116)
  • PEX13 (9031)
  • pex13 (7955)
  • CG4663 (7227)
  • AgaP_AGAP010074 (7165)
  • prx-13 (6239)
  • PEX13 (4932)
  • KLLA0E19735g (28985)
  • AGOS_ACR230C (33169)
  • GeneID:2674186 (148305)
  • NCU02618 (5141)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit