Denigma

paa-1

Symbol: paa-1
Name: Phosphatase 2A regulatory A subunit
Alias: Phosphatase 2A regulatory A subunit family member (paa-1);WBGENE00003901
Entrez gene ID: 175750
Ensembl gene ID: F48E8.5
Species: Worm (Taxid: 6239)

Functional description:
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (By similarity). [UniProt]

Observation:

paa-1 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • paa-1 RNAi

    • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PPP2R1A (9606)
  • PPP2R1A (9598)
  • PPP2R1A (9615)
  • PPP2R1A (9913)
  • Ppp2r1a (10090)
  • Ppp2r1a (10116)
  • Pp2A-29B (7227)
  • AgaP_AGAP009105 (7165)
  • paa-1 (6239)
  • paa1 (4896)
  • TPD3 (4932)
  • KLLA0F07689g (28985)
  • AGOS_ACR279C (33169)
  • GeneID:2676002 (148305)
  • NCU00488 (5141)
  • PP2AA2 (3702)
  • PP2AA3 (3702)
  • Os09g0249700 (4530)



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