gpr-2

Symbol: gpr-2
Name: G Protein Regulator
Alias: G Protein Regulator family member (gpr-2);WBGENE00001689
Entrez gene ID: 176318
Ensembl gene ID: C38C10.4
Species: Worm (Taxid: 6239)

Functional description:
Complex of gpr-1 and gpr-2, in association with lin-5, activates G-protein signaling to affect mitotic spindle force. Polarity determinants (par genes) may regulate lin-5/gpr-1/gpr- 2/goa-1 locally to create the asymmetric forces that drive spindle movement. [UniProt]

Observation:

gpr-2 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • gpr-2 RNAi

  • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • gpr-1 (6239)
  • gpr-2 (6239)



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