Denigma

rpa-1

Symbol: rpa-1
Name: Replication Protein A homolog 1
Alias: Replication Protein A homolog family member (rpa-1);WBGENE00017546
Entrez gene ID: 174238
Ensembl gene ID: F18A1.5
Species: Worm (Taxid: 6239)

Functional description:
Binds to single-stranded sequences participating in DNA replication (By similarity). [UniProt]

Observation:

rpa-1 RNAi in the adulthood extends the mean and maximum lifespan by 5 and 22%, respectively [23144747].



Interventions:
  • rpa-1 RNAi +5.1% +21.7%

    • Assays: Organismal Lifespan
    Mean: +5.1
    Maximum: +21.7

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • References:
  • 23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • rpa-1 (6239)
  • AT5G61000 (3702)
  • RPA70B (3702)
  • Os03g0214100 (4530)



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