rpn-7

Symbol: rpn-7
Name: proteasome Regulatory Particle, Non-ATPase-like
Alias: WBGene00004463
Entrez gene ID: 177753
Ensembl gene ID: F49C12.8
Species: Worm (Taxid: 6239)

Functional description:
rpn-7 is predicted to encode a non-ATPase subunit of the 19S regulatory complex of the proteasome that affects fertility and embryonic viability.; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). [UniProt]

Observation:

rpn-7 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • rpn-7 RNAi

  • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PSMD6 (9606)
  • PSMD6 (9598)
  • PSMD6 (9615)
  • PSMD6 (9913)
  • Psmd6 (10090)
  • Psmd6 (10116)
  • PSMD6 (9031)
  • psmd6 (7955)
  • Rpn7 (7227)
  • AgaP_AGAP002061 (7165)
  • rpn-7 (6239)
  • AT4G24820 (3702)
  • Os02g0600100 (4530)
  • Os04g0485000 (4530)



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