F54D5.11

Symbol: F54D5.11
Alias: WBGene00009542
Entrez gene ID: 177779
Ensembl gene ID: F54D5.11
Species: Worm (Taxid: 6239)

Functional description:
in mass RNAi assays, F38E11.5 is required for fertility and general health.; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). [UniProt]

Observation:

F38E11.5 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • F38E11.5 RNAi

  • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • COPB2 (9606)
  • COPB2 (9598)
  • COPB2 (9615)
  • COPB2 (9913)
  • Copb2 (10090)
  • COPB2 (9031)
  • copb2 (7955)
  • beta'Cop (7227)
  • AgaP_AGAP004798 (7165)
  • F38E11.5 (6239)
  • sec27 (4896)
  • SEC27 (4932)
  • KLLA0B01958g (28985)
  • AGOS_AFL118W (33169)
  • GeneID:2682116 (148305)
  • NCU07319 (5141)
  • AT3G15980 (3702)
  • AT1G79990 (3702)
  • AT1G52360 (3702)
  • Os06g0143900 (4530)



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