vha-2

Symbol: vha-2
Name: Vacuolar H ATPase
Alias: WBGene00006911
Entrez gene ID: 187779
Ensembl gene ID: R10E11.2
Species: Worm (Taxid: 6239)

Functional description:
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [UniProt]

Observation:

RNAi against vha-2 starting in the adulthood decreases the lifespan [New longevity regulators].



Interventions:
  • vha-2 RNAi

  • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • Vha16-3 (7227)
  • vha-2 (6239)
  • vha-3 (6239)
  • AVA-P2 (3702)
  • AVA-P4 (3702)
  • ATVHA-C3 (3702)
  • AVA-P1 (3702)
  • AT2G16510 (3702)
  • Os02g0550100 (4530)
  • Os05g0106100 (4530)
  • Os11g0169900 (4530)
  • Os12g0168900 (4530)
  • PFE0965c (5833)



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