Symbol: cdtl-7 Name: CDc-Two Like 7 Entrez gene ID: 175559 Ensembl gene ID: B0285.1 Species: Worm (Taxid: 6239) Functional description: Cyclin-dependent kinase which displays CTD kinase activity: hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit, thereby acting as a key regulator of transcription elongation (By similarity). [UniProt] Observation: RNAi against cdtl-7 starting in the adulthood decreases mean and maximum lifespan by 22 and 25%, respectively [23144747]. Interventions: Assays: Organismal Lifespan Mean: -22.2 Maximum: -25.0 Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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