Denigma

wis1

Symbol: wis1
Alias: spc2; smf2
Entrez gene ID: 2541055
Ensembl gene ID: SPBC409.07c
Species: (Taxid: 4896)

Functional description:
MAP kinase kinase Wis1

Observation:

Constitutive active mutation of wis1 extends chronological lifespan and there is no further beneficial effect of DR [20075862].



Interventions:
  • wis1 constitutive active mutation

    • Assays: Chronological Lifespan

    Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor
  • DR-Essential


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • MAP2K4 (9606)
  • MAP2K4 (9598)
  • MAP2K4 (9615)
  • MAP2K4 (9913)
  • Map2k4 (10090)
  • Map2k4 (10116)
  • MAP2K4 (9031)
  • map2k4 (7955)
  • Mkk4 (7227)
  • AgaP_AGAP003365 (7165)
  • mkk-4 (6239)
  • VZC374L.1 (6239)
  • wis1 (4896)
  • PBS2 (4932)
  • KLLA0E15313g (28985)
  • AGOS_AFL217C (33169)
  • GeneID:2681821 (148305)
  • NCU00587 (5141)

    • Orthologs
  • PBS2 (4932)
  • Map2k4 (10116)
  • VZC374L.1 (6239)
  • MAP2K4 (9606)
  • mkk-4 (6239)
  • Mkk4 (7227)
  • Map2k4 (10090)
  • PBS2 (4932)
  • Map2k4 (10116)
  • VZC374L.1 (6239)
  • MAP2K4 (9606)
  • mkk-4 (6239)
  • Mkk4 (7227)
  • Map2k4 (10090)



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