Symbol: CG11015 Entrez gene ID: 33918 Ensembl gene ID: FBgn0039044 Species: Fly (Taxid: 7227) Functional description: CG11015 gene product from transcript CG11015-RA; The gene Cytochrome c oxidase subunit Vb is referred to in FlyBase by the symbol Dmel\CoVb (CG11015, FBgn0031830). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cytochrome-c oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process: mitochondrial electron transport, cytochrome c to oxygen. 5 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Cytochrome c oxidase, subunit Vb. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [FlyBase] Observation: CG11015 is translational upregulated upon DR. Under rich nutritional conditions lifespan of CG11015 RNAi treated animals is indistinguishable from that of controls, while upon DR, lifespan extension is diminished in males and females [19804760]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Orthologs Inparanoids Edit \ Update (Admin) | Delete |
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