HXT17

Symbol: HXT17
Name: HeXose Transporter 17
Entrez gene ID: 855809
Ensembl gene ID: YNR072W
Species: Yeast (Taxid: 4932)

Functional description:
Hxt17p; Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose [Source:SGD;Acc:S000005355] [Ensembl]

Observation:

HXT17 mutation extends both replicative and chronological lifespan as well as cancels out DR-induced replicative and chronological lifespan extension. Mean and maximum replicative lifespan are extended by 27 and 49%, respectively [21584246].



Interventions:
  • HXT17 deletion +27% +49%

  • Assays: Replicative Lifespan Chronological Lifespan
    Mean: +27
    Maximum: +49

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • HXT16 (4932)
  • HXT15 (4932)
  • HXT13 (4932)
  • HXT17 (4932)
  • MSS1 (3702)
  • Os03g0218400 (4530)

  • Orthologs
  • (4932)
  • SNF3 (4932)
  • MPH2 (4932)
  • HXT15 (4932)
  • MAL31 (4932)
  • HXT4 (4932)
  • HXT1 (4932)
  • HXT5 (4932)
  • STL1 (4932)
  • HXT13 (4932)
  • MPH3 (4932)
  • (4932)
  • GAL2 (4932)
  • MAL11 (4932)
  • RGT2 (4932)
  • HXT8 (4932)
  • HXT14 (4932)
  • HXT7 (4932)
  • HXT6 (4932)
  • HXT3 (4932)
  • HXT2 (4932)
  • HXT10 (4932)
  • HXT9 (4932)
  • HXT16 (4932)
  • HXT11 (4932)



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