RCR2

Symbol: RCR2
Name: Resistance to Congo Red 2
Alias: SSH5
Entrez gene ID: 851566
Ensembl gene ID: YDR003W
Species: Yeast (Taxid: 4932)

Functional description:
Rcr2p; Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane; similar to Rcr1p [Source:SGD;Acc:S000002410] [Ensembl]

Observation:

RCR2 deletion extends mean replicative lifespan by 18% and cancels out the lifespan extending effect of DR [22912585].



Interventions:
  • RCR2 deletion +18% -4%

  • Assays: Replicative Lifespan
    Mean: +18
    Maximum: -4

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • RCR1 (4932)
  • RCR2 (4932)
  • KLLA0E17447g (28985)

  • Orthologs
  • RCR1 (4932)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit