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Symbol: GTR1 Name: GTp binding protein Resemblance 1 Entrez gene ID: 854918 Ensembl gene ID: YML121W Species: Yeast (Taxid: 4932) Functional description: Gtr1p; Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB [Source:SGD;Acc:S000004590] [Ensembl] Observation: GTR1 deletion decreases mean and maximum replicative lifespan under AL by 36 and 51%, respectively, and cancels out the lifespan extending effect of DR [22912585]. Interventions: Assays: Replicative Lifespan Mean: -36 Maximum: -51 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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