VPS51

Symbol: VPS51
Name: Vacuolar Protein Sorting 51
Alias: WHI6;API3;VPS67
Entrez gene ID: 853890
Ensembl gene ID: YKR020W
Species: Yeast (Taxid: 4932)

Functional description:
Vps51p; Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p [Source:SGD;Acc:S000001728] [Ensembl]

Observation:

Deletion of VPS51 increases mean chronological lifespan by 6 - 10% (6, 7, 8, 9, 10) in diploid cells [21447998].



Assays:
Mean: +6-10

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • VPS51 (4932)
  • KLLA0D02200g (28985)



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