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Symbol: MTO1 Name: Mitochondrial Translation Optimization 1 Alias: IPS1 Entrez gene ID: 852616 Ensembl gene ID: YGL236C Species: Yeast (Taxid: 4932) Functional description: Mto1p; Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants [Source:SGD;Acc:S000003205] [Ensembl] Observation: Deletion of MTO1 increases mean chronological lifespan by 16 - 92% (16, 23, 26, 92) in diploid cells [21447998]. Assays: Mean: +16-92 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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