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Symbol: GPA1 Name: G Protein Alpha subunit 1 Alias: CDC70;DAC1;SCG1 Entrez gene ID: 856394 Ensembl gene ID: YHR005C Species: Yeast (Taxid: 4932) Functional description: Gpa1p; GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome [Source:SGD;Acc:S000001047] [Ensembl] Observation: Deletion of GPA1 increases mean chronological lifespan by 34 - 127% (34, 36, 43, 69, 127) in diploid cells [21447998]. Assays: Mean: +34-127 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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