Denigma: Factor

CTF8

Symbol: CTF8
Name: Chromosome Transmission Fidelity 8
Entrez gene ID: 856598
Ensembl gene ID: YHR191C
Species: Yeast (Taxid: 4932)

Functional description:
Ctf8p; Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion [Source:SGD;Acc:S000001234] [Ensembl]

Observation:

Deletion of CTF8 increases mean chronological lifespan by 15-92% (15, 18, 42, 45, 92) in diploid cells [21447998].

Interventions:

CTF8 deletion +15 to +92%

Assays: Chronological Lifespan
Mean: +15-92

Classification:

Gerontogene

Positive Gerontogene

Aging Relevance Analysis/Source:

GenAge