Symbol: ACO1 Name: ACOnitase 1 Alias: GLU1 Entrez gene ID: 851013 Ensembl gene ID: YLR304C Species: Yeast (Taxid: 4932) Functional description: Aco1p; Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy [Source:SGD;Acc:S000004295] [Ensembl] Observation: Deletion of ACO1 decreases mean chronological lifespan by 42 - 56% in diploid cells [21447998]. Interventions: Assays: Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit