CTT1

Symbol: CTT1
Name: CaTalase T 1
Alias: SPS101
Entrez gene ID: 852979
Ensembl gene ID: YGR088W
Species: Yeast (Taxid: 4932)

Functional description:
Ctt1p; Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide [Source:SGD;Acc:S000003320] [Ensembl]

Observation:

Overexpression of cytosolic catalase T CTT1 alone slightly shortens stationary phase survival in strain DBY746. Overexpression CTT1 in combination with SOD1 increases stationary phase survival by about 10% [12586694]. Mutational inactivation [20696905] or deletion [21076178] of CTT1 lead to a longer chronological lifespan.



Interventions:
  • CTT1 mutation
  • CTT1 deletion
  • CTT1 overexpression

  • Assays: Chronological Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CTT1 (4932)
  • KLLA0D14685g (28985)

  • Note: Is CTT1 a negative Gerontogene and Positive Aging-Suppressor Gene?

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