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Symbol: RPT5 Name: Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 5 Alias: YTA1 Entrez gene ID: 854284 Ensembl gene ID: YOR117W Species: Yeast (Taxid: 4932) Functional description: Rpt5p; One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription; similar to human TBP1 [Source:SGD;Acc:S000005643] [Ensembl] Observation: Mutation of RPT5 decreases mean (-85%) and maximum (-81%) replicative lifespan [21931558]. Assays: Mean: -85 Maximum: -81 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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