RPT3

Symbol: RPT3
Name: Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 3
Alias: YNT1;YTA2
Entrez gene ID: 852003
Ensembl gene ID: YDR394W
Species: Yeast (Taxid: 4932)

Functional description:
Rpt3p; One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B [Source:SGD;Acc:S000002802] [Ensembl]

Observation:

Mutation of RPT3 decreases mean (-55%) and maximum (-42%) replicative lifespan [21931558].



Assays:
Mean: -55
Maximum: -42

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PSMC4 (9606)
  • PSMC4 (9598)
  • PSMC4 (9615)
  • PSMC4 (9913)
  • Psmc4 (10090)
  • Psmc4 (10116)
  • psmc4 (7955)
  • Rpt3 (7227)
  • AgaP_AGAP003008 (7165)
  • rpt-3 (6239)
  • rpt3 (4896)
  • RPT3 (4932)
  • KLLA0C06534g (28985)
  • AGOS_AFR394W (33169)
  • GeneID:2674662 (148305)
  • NCU02260 (5141)
  • RPT3 (3702)
  • Os02g0325100 (4530)
  • PFD0665c (5833)



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