NOP12

Symbol: NOP12
Name: NucleOlar Protein
Entrez gene ID: 854116
Ensembl gene ID: YOL041C
Species: Yeast (Taxid: 4932)

Functional description:
Nop12p; Nucleolar protein involved in pre-25S rRNA processing and biogenesis of large 60S ribosomal subunit; contains an RNA recognition motif (RRM); binds to Ebp2; similar to Nop13p and Nsr1p [Source:SGD;Acc:S000005401] [Ensembl]

Observation:

Deletion of NOP12 increased mean (25.1 -> 36.7) and maximum replicative lifespan in BY4742 [18423200].



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • RBM34 (9606)
  • RBM34 (9598)
  • RBM34 (9615)
  • Rbm34 (10090)
  • Rbm34 (10116)
  • RBM34 (9031)
  • RBM34 (9031)
  • rbm34 (7955)
  • F11A10.7 (6239)
  • nop12 (4896)
  • NOP12 (4932)
  • KLLA0F07799g (28985)
  • AGOS_ACR274W (33169)
  • AT5G46840 (3702)
  • Os03g0854300 (4530)



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