Gsta4

Symbol: Gsta4
Name: glutathione S-transferase, alpha 4
Alias: GST5
Entrez gene ID: 14860
Ensembl gene ID: ENSMUSG00000032348
Species: Mouse (Taxid: 10090)

Functional description:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. [UniProt]

Observation:

Gsta4 null mice, had impaired 4-hydroxynonenal detoxification, but extended average lifespan.



Assays: Organismal Lifespan

Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • LOC610304 (9615)
  • GSTA3 (9913)
  • Gsta4 (10090)
  • Gsta4 (10116)
  • RGD1564906 (10116)
  • GSTA (9031)
  • LOC396380 (9031)
  • GSTA3 (9031)
  • zgc:173962 (7955)
  • zgc:173961 (7955)
  • gstal (7955)

  • Inparanoids
  • ENSMUSP00000034903 (10090)
  • ENSRNOP00000012346 (10116)



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