Denigma: Factor

UGA3

Symbol: UGA3
Name: Utilization of GAba 3
Entrez gene ID: 851384
Ensembl gene ID: YDL170W
Species: Yeast (Taxid: 4932)

Functional description:
Uga3p; Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus [Source:SGD;Acc:S000002329] [Ensembl]

Observation:

Deletion of UGA3 increases mean and maximum replicative lifespan by 75% and 63%, respectively [20550517]

Interventions:

UGA3 deletion +75% +63%

Assays: Replicative Lifespan
Mean: +75
Maximum: +63

Classification:

Gerontogene

Positive Gerontogene

Aging Relevance Analysis/Source:

GenAge