Symbol: YME1 Name: Yeast Mitochondrial Escape 1 Entrez gene ID: 856135 Ensembl gene ID: YPR024W Species: Yeast (Taxid: 4932) Functional description: Yme1p; Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover [Source:SGD;Acc:S000006228] [Ensembl] Observation: Deletion of YME1 decreases chronological lifespan by 50% [17492370] as well as replicative lifespan by 45% in the alpha strain [18340043]. Interventions: Assays: Replicative Lifespan Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit