GMC2

Symbol: GMC2
Name: Grand Meiotic recombination Cluster 2
Entrez gene ID: 851166
Ensembl gene ID: YLR445W
Species: Yeast (Taxid: 4932)

Functional description:
hypothetical protein; Putative protein of unknown function; transcription is regulated by Ume6p and induced in response to alpha factor [Source:SGD;Acc:S000004437] [Ensembl]; Protein involved in meiotic progression; mutants are delayed in meiotic nuclear division and are defective in synaptonemal complex assembly; transcription is regulated by Ume6p and induced in response to alpha factor [SGD]

Observation:

Deletion of GMC2 decreases replicative lifespan by 50% in the alpha strain [19030232].



Interventions:
  • GMC2 deletion -50%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • YLR445W (4932)
  • KLLA0B04928g (28985)
  • AGOS_AER137W (33169)



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