YKL069W

Symbol: YKL069W
Alias: fRMsr; YKG9
Entrez gene ID: 853794
Ensembl gene ID: YKL069W
Species: Yeast (Taxid: 4932)

Functional description:
green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; hypothetical protein; Methionine-R-sulfoxide reductase, reduces the R enantiomer of free Met-SO, in contrast to Ycl033Cp which reduces Met-R-SO in a peptide linkage; has a role in protection against oxidative stress [Source:SGD;Acc:S000001552] [Ensembl]

Observation:

Deletion of YKL069W increases sensitivity to oxidative stress and decreases replicative lifespan [19049972].



Interventions:
  • YKL069W deletion

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • YKL069W (4932)
  • KLLA0F26587g (28985)
  • AGOS_AFR115W (33169)
  • GeneID:2683226 (148305)
  • NCU01163 (5141)



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