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Symbol: YFH1 Name: Yeast Frataxin Homolog 1 Entrez gene ID: 851437 Ensembl gene ID: YFH1 Species: Yeast (Taxid: 4932) Functional description: Yfh1p; Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog is mutated in Friedrich's ataxia [Source:SGD;Acc:S000002278] [Ensembl] Observation: Deletion of YFH1 decreases replicative lifespan by 50% [15130665]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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