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Symbol: CKIepsilon Name: casein kinase I epsilon Alias: tau Species: Hamster (Taxid: 10036) Functional description: Can phosphorylate a number of proteins, including circadian rhythm proteins Observation: A mutation called tau, if homozygous, shortens the circadian period (by 20%), increases metabolic rate (by 20%), and increases lifespan by 14-16% under conditions of constant darkness [12054192]. Male and female wild-type hamsters are heavier than homozygous mutants throughout the entire lifespan, and heterozygous mutants have intermediate weight [12054192]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRNote: Get Genid! Edit \ Update (Admin) | Delete |
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