TPC1

Symbol: TPC1
Name: Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family
Entrez gene ID: 852988
Species: Yeast (Taxid: 4932)

Functional description:
Tpc1p; Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family [Source:SGD;Acc:S000003328] [Ensembl]

Observation:

Replicative lifespan decreased by 20% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SLC25A19 (9606)
  • SLC25A19 (9598)
  • SLC25A19 (9615)
  • SLC25A19 (9913)
  • Slc25a19 (10090)
  • Slc25a19 (10116)
  • SLC25A19 (9031)
  • zgc:111878 (7955)
  • CG6608 (7227)
  • AgaP_AGAP005113 (7165)
  • AgaP_AGAP006806 (7165)
  • C42C1.10 (6239)
  • SPBC1604.04 (4896)
  • TPC1 (4932)
  • KLLA0D15015g (28985)
  • AGOS_AAR036W (33169)
  • GeneID:2674933 (148305)
  • NCU07384 (5141)
  • AT5G48970 (3702)
  • AT3G21390 (3702)
  • Os01g0934200 (4530)
  • PF13_0359 (5833)



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