TIF2

Symbol: TIF2
Name: Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
Entrez gene ID: 853303
Species: Yeast (Taxid: 4932)

Functional description:
Tif2p; Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G [Source:SGD;Acc:S000003674] [Ensembl]

Observation:

Replicative lifespan increased by 35% in the alpha strain and 15% in the a strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • EIF4A1 (9606)
  • EIF4A1 (9615)
  • EIF4A1 (9913)
  • Eif4a1 (10090)
  • Eif4a1 (10116)
  • eif4a1b (7955)
  • eif4a1a (7955)
  • inf-1 (6239)
  • SPAC1006.07 (4896)
  • TIF2 (4932)
  • TIF1 (4932)
  • KLLA0A05731g (28985)
  • AGOS_ACR253C (33169)
  • GeneID:2677872 (148305)
  • NCU07420 (5141)
  • AT1G72730 (3702)



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