TFP1

Symbol: TFP1
Name: Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease
Entrez gene ID: 851342
Species: Yeast (Taxid: 4932)

Functional description:
Vma1p; Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease [Source:SGD;Acc:S000002344] [Ensembl]

Observation:

Replicative lifespan decreased by 30% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • atp6v1al (7955)
  • atp6v1a (7955)
  • Vha68-1 (7227)
  • vma1 (4896)
  • TFP1 (4932)
  • KLLA0F05401g (28985)
  • GeneID:2678289 (148305)
  • NCU01207 (5141)
  • VHA-A (3702)
  • Os06g0662000 (4530)
  • Os02g0175400 (4530)
  • vapA (5833)



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