SWF1

Symbol: SWF1
Name: Spore Wall Formation 1
Entrez gene ID: 851704
Ensembl gene ID: YDR126W
Species: Yeast (Taxid: 4932)

Functional description:
Swf1p; Palmitoyltransferase that acts on transmembrane proteins, including the SNAREs Snc1p, Syn8p, Tlg1p and likely all SNAREs; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion [Source:SGD;Acc:S000002533] [Ensembl]

Observation:

Deletion of SWF1 decreases replicative lifespan by 30% in the alpha strain [19030232; 18340043].



Interventions:
  • SWF1 deletion -30%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SWF1 (4932)
  • KLLA0F19690g (28985)
  • AGOS_AGR065W (33169)



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