Denigma

SWD1

Symbol: SWD1
Name: Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
Entrez gene ID: 851265
Species: Yeast (Taxid: 4932)

Functional description:
Swd1p; Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7 [Source:SGD;Acc:S000000064] [Ensembl]

Observation:

Replicative lifespan decreased by 20% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • RBBP5 (9606)
  • RBBP5 (9598)
  • RBBP5 (9615)
  • RBBP5 (9913)
  • Rbbp5 (10090)
  • Rbbp5 (10116)
  • RBBP5 (9031)
  • rbbp5 (7955)
  • CG5585 (7227)
  • AgaP_AGAP010575 (7165)
  • F21H12.1 (6239)
  • swd1 (4896)
  • SWD1 (4932)
  • KLLA0A08800g (28985)
  • AGOS_AFL006C (33169)
  • GeneID:2678091 (148305)
  • NCU02104 (5141)
  • AT3G21060 (3702)
  • Os03g0207900 (4530)



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