SOK1

Symbol: SOK1
Name: Suppressor Of Kinase 1
Entrez gene ID: 851569
Species: Yeast (Taxid: 4932)

Functional description:
Sok1p; Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 [Source:SGD;Acc:S000002413] [Ensembl]

Observation:

Deletion of SOK1 increases replicative lifespan by 50 - 20% in the alpha and a strains [19030232] as well as mean chronological lifespan by 19 - 51% (19, 19, 23, 51) in diploid cells [21447998].



Assays:
Mean: +19-51

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SOK1 (4932)
  • KLLA0E17579g (28985)
  • AGOS_AER011C (33169)



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