Symbol: SOK1 Name: Suppressor Of Kinase 1 Entrez gene ID: 851569 Species: Yeast (Taxid: 4932) Functional description: Sok1p; Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 [Source:SGD;Acc:S000002413] [Ensembl] Observation: Deletion of SOK1 increases replicative lifespan by 50 - 20% in the alpha and a strains [19030232] as well as mean chronological lifespan by 19 - 51% (19, 19, 23, 51) in diploid cells [21447998]. Assays: Mean: +19-51 Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit