SIP1

Symbol: SIP1
Name: SNF1-Interacting Protein 1
Entrez gene ID: 852032
Ensembl gene ID: YDR422C
Species: Yeast (Taxid: 4932)

Functional description:
Sip1p; Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions [Source:SGD;Acc:S000002830] [Ensembl]

Observation:

Deletion of SIP1 decreases replicative lifespan by 80%, without accompying aging biomarkers in S288C strain [10921902].



Interventions:
  • SIP1 deletion -80%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SIP1 (4932)
  • AGOS_ADR194C (33169)



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