Denigma

SAC1

Symbol: SAC1
Name: Suppressor of ACtin 1
Alias: RSD1
Entrez gene ID: 853668
Ensembl gene ID: YKL212W
Species: Yeast (Taxid: 4932)

Functional description:
Sac1p; Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance [Source:SGD;Acc:S000001695] [Ensembl]

Observation:

Deletion of SAC1 decreases replicative lifespan by 40% in the alpha strain [18340043].



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • SACM1L (9606)
  • SACM1L (9598)
  • SACM1L (9615)
  • SACM1L (9913)
  • Sacm1l (10090)
  • Sacm1l (10116)
  • SACM1L (9031)
  • si:ch211-222e23.8 (7955)
  • zgc:158642 (7955)
  • Sac1 (7227)
  • AgaP_AGAP000891 (7165)
  • F30A10.6 (6239)
  • SPBC19F5.03 (4896)
  • SAC1 (4932)
  • KLLA0B14388g (28985)
  • AGOS_AER447C (33169)
  • GeneID:5051248 (148305)
  • NCU00896 (5141)
  • RHD4 (3702)
  • ATSAC1B (3702)
  • Os02g0554300 (4530)
  • Os11g0309000 (4530)



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