RPL7A

Symbol: RPL7A
Name: Ribosomal Protein of the Large subunit 7A
Alias: L6A;L7A;YL8;rp11
Entrez gene ID: 852804
Ensembl gene ID: YGL076C
Species: Yeast (Taxid: 4932)

Functional description:
Rpl7ap; Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2) [Source:SGD;Acc:S000003044] [Ensembl]

Observation:

Deletion of RPL7A increases mean replicative lifespan by 40% in the alpha strain and 20% in a strain [18423200] and by 31% in the ORF collection, but non-significantly in the remade strain [22377630].



Assays:
Mean: +20-40

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • LOC744947 (9598)
  • RPL7 (9615)
  • RPL7 (9913)
  • RPL7 (9913)
  • Gm5045 (10090)
  • RPL7 (9031)
  • rpl7 (7955)
  • RpL7 (7227)
  • AgaP_AGAP008916 (7165)
  • rpl701 (4896)
  • rpl702 (4896)
  • RPL7A (4932)
  • RPL7B (4932)
  • KLLA0D03410g (28985)
  • AGOS_AFL082W (33169)
  • GeneID:2675441 (148305)
  • NCU07829 (5141)
  • AT2G44120 (3702)
  • AT2G01250 (3702)
  • AT3G13580 (3702)
  • Os08g0234000 (4530)
  • Os04g0605900 (4530)

  • Note: Increases mean RLS non-significantly in the remade strain.

    Edit \ Update (Admin) | Delete

    Comment on This Data Unit