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Symbol: Cebpa Name: CCAAT/enhancer binding protein (C/EBP), alpha Alias: C/EBPalpha Entrez gene ID: 12606 Ensembl gene ID: ENSMUSG00000034957 Species: Mouse (Taxid: 10090) Functional description: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. [UniProt] Observation: Replacing the Cebpa gene by Cebpb increases mean lifespan by about 20% [15289464]. C/ebpalpha(beta/beta) animals consume more food but weight less than controls [10982846], and have a slightly elevated body temperature (0.3-0.5 degree Celsius) [15289464]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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