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Symbol: RPL19B Name: Ribosomal Protein of the Large subunit 19B Alias: L19B;L23B;YL14;rpl5L Entrez gene ID: 852254 Ensembl gene ID: YBL027W Species: Yeast (Taxid: 4932) Functional description: Rpl19bp; Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Ap and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal [Source:SGD;Acc:S000000123] [Ensembl] Observation: Deletion of RPL19B increases mean replicative lifespan 15 - 20% in the alpha strain [18340043; 18423200] and non-significantly by 10 in the ORF collection as well as by 46% in the remade strain [22377630]. Its deletion also increases mean chronological lifespan by 47 - 67% (47, 47, 67) in diploid cells [21447998]. Assays: Mean: +15-67 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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