PDA1

Symbol: PDA1
Name: E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose
Entrez gene ID: 856925
Species: Yeast (Taxid: 4932)

Functional description:
Pda1p; E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose [Source:SGD;Acc:S000000980] [Ensembl]

Observation:

Replicative lifespan decreased by 20% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PDHA2 (9606)
  • PDHA2 (9598)
  • PDHA2 (9913)
  • Pdha2 (10090)
  • Pdha2 (10116)
  • AgaP_AGAP004786 (7165)
  • AgaP_AGAP004773 (7165)
  • T05H10.6 (6239)
  • pda1 (4896)
  • PDA1 (4932)
  • KLLA0F12001g (28985)
  • AGOS_AGR103W (33169)
  • GeneID:2684526 (148305)
  • NCU06482 (5141)
  • IAR4 (3702)
  • AT-E1_ALPHA (3702)
  • Os02g0739600 (4530)
  • Os06g0246500 (4530)



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